I don't feel the same here about Mike, I think he's got more friends than people seem to realize.
In
"Garbageman" : The professor even though a good friend of Don, cares about Mike enough to save him a comic book. People who just humor others wouldn't go out of their way to save things they know the people like.
Now with the Silver Sentry, in
"The unconvincing Turtle Titan" he did look down at Michelangelo and humor him at the beginning. Though by the end of the episode Mike did earn his respect. So much so that he came for their Christmas Dinner (when I'm sure such a big hero could of had many other invites he could of went to instead. Than in
"Clash of the Turtle Titans" we learn just how much Silver Sentry cared for and looked up to Mike, by his grandson taking on the Turtle Titan name. That shows that there was just more than humor or just being amused. I do feel that Mikey did touch Silver Sentry and earned real respect.
Of course there's always
"Return of the Justice Force" where Mike seems like a fan boy at first but does end up saving the day and once again earning respect, enough respect to be put into a comic book.
And how can we forget Nobody, sure he doesn't seem like he is a close friend but in
"Still Nobody" it wasn't Leonardo that Nobody called when he needed help, it was Michelangelo. That's saying something right there.
True there's not a lot of people in the Turtle's life would respect him from the minute they meet him, though Mike does earn friendships and respect down the road with most anyone who meets him. Not just humor and being looked down upon. There's a lot more examples through out the series of people that Michelangelo has touched. Like Cody, they play video games together and get excited over stuff together. April and Casey both have shown they like Mike in more than just the annoyance way... like April helping him with his costume. True it's easy to over look it that Mike has friends, though he does. And really if he had someone just like him in the crowd it'd drive him nuts because they'd be clashing for attention.
A good example of that goes back to the original series with the episode "Cowabunga ShredHead".